![]() ![]() So, if you are struggling with erectile dysfunction, should you be worried about trying Viagra? In short, no. In addition, taking the drug under medical supervision would likely have meant that the men would not have used such a high dose on their first time. Starting with a lower dose may have meant less severe side-effects. These men also took the highest recommended dose of sildenafil on their first time taking the drug. So, why were these men susceptible to such long-lived side-effects? It may be possible that a small subsection of the population does not break sildenafil down and eliminate it from the body efficiently, leading to very high concentrations in the blood compared with most users. However, I wanted to highlight that persistent eye and vision problems may be encountered for a small number of users." ![]() "For the vast majority of men, any side-effects will be temporary and mild. "Many men use non-prescription performance enhancing drugs to help with sexual anxiety and erectile dysfunction," said Karaarslan. Fortunately, in all 17 patients the symptoms had cleared up by 21 days later, but this was doubtless a difficult experience for the men involved. The doctors in the clinic conducted various eye tests and monitored the patients over time to see how their symptoms developed. The visual side-effects began once the drug took effect, and were still present when the men arrived at the clinic 24-48 hours later. None of the men had been prescribed the medication. ![]() In the new study, Karaarslan reports that the patients suffered numerous visual disturbances, including abnormally dilated pupils, blurred vision, light sensitivity, and color vision disturbances, which included intensely blue colored vision with red/green color blindness.Īll 17 patients had taken sildenafil for the first time, and all took the highest recommended dose of 100 mg. Cüneyt Karaarslan of the Dünyagöz Adana hospital in Turkey, noticed a pattern in 17 male patients who attended the hospital. The effects of the drug normally last 3-5 hours and although side-effects such as headache and blurred vision occasionally occur, they usually disappear relatively quickly. Originally developed as a treatment for high blood pressure, the drug dilates blood vessels and relaxes smooth muscle in the penis, making it easier to achieve and maintain an erection. It soon became the fastest selling drug in history, demonstrating the phenomenal demand for treatments that enhance sexual performance. Sildenafil, more commonly known by its tradename Viagra, became available in 1998 as a treatment for erectile dysfunction. While these effects appear to be rare, the research suggests that first-time Viagra users should start with a lower dose before increasing it, if necessary.Įrectile dysfunction can have significant psychological consequences for men who are affected by it, and it can make fulfilling sexual relationships more difficult to achieve. However, a recent study in Frontiers in Neurology has highlighted the risk of persistent visual side-effects, such as light sensitivity and color vision impairment, in men who have taken the highest recommended dose of Viagra. Sildenafil is commonly used to treat erectile dysfunction and is generally regarded as safe with limited side effects. ![]()
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![]() ![]() ![]() Overusing our search engine with a very large number of searches in a very short amount of time.Using a badly configured (or badly written) browser add-on for blocking content.Running a "scraper" or "downloader" program that either does not identify itself or uses fake headers to elude detection.Using a script or add-on that scans GameFAQs for box and screen images (such as an emulator front-end), while overloading our search engine. ![]() There is no official GameFAQs app, and we do not support nor have any contact with the makers of these unofficial apps. Continued use of these apps may cause your IP to be blocked indefinitely. This triggers our anti-spambot measures, which are designed to stop automated systems from flooding the site with traffic. Some unofficial phone apps appear to be using GameFAQs as a back-end, but they do not behave like a real web browser does.Using GameFAQs regularly with these browsers can cause temporary and even permanent IP blocks due to these additional requests. If you are using the Brave browser, or have installed the Ghostery add-on, these programs send extra traffic to our servers for every page on the site that you browse, then send that data back to a third party, essentially spying on your browsing habits.We strongly recommend you stop using this browser until this problem is corrected. The latest version of the Opera browser sends multiple invalid requests to our servers for every page you visit.The most common causes of this issue are: Continued abuse of our services will cause your IP address to be blocked indefinitely.Your IP address has been temporarily blocked due to a large number of HTTP requests. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior. Your IP address has been temporarily blocked due to a large number of HTTP requests. ![]() ![]() Secondly, if left untreated, keratin granulations can open the door to toenail fungus (see above). ![]() Prolonged use of nail polish – as well as acetone-based nail polish removers – dries out the surface of your toenails and can lead to these keratin granulations. Keratin granulations are dehydrated superficial layers of nail cells that result in white, rough, and uneven dry patches on the top of the nail. There are a couple of reasons why.įirst of all, these white, chalky toenails are the result of keratin granulations on the surface of your toenails. ![]() While the presence of these spots isn’t serious, they are a sign it’s time to give the polish a break. This reaction is understandable – but these spots are common for anyone who overuses toenail polish. If you’ve ever removed your toenail polish to find white spots on your nails, you might have been a bit alarmed at the sudden change in your nails. Do you have white spots on your toenails after removing polish? To truly know what’s causing your symptoms (including white nails), your doctor will most likely run bloodwork to check your levels before devising a treatment plan. ![]() While it may seem obvious to self-treat a perceived deficiency with mineral supplements, doing so can be detrimental to your health and can even lead to a dangerous overdose. In either case, it’s important to see a medical professional if you suspect you have a mineral deficiency. While mineral deficiencies’ effects on the nails are common, you will typically notice other symptoms of an iron or zinc deficiency before you see a white nail. Both iron deficiency anemia and zinc deficiency can cause white nails that are thin and brittle. If most of a toenail appears white – except for the tip – you may have a mineral deficiency that is causing the discoloration. In addition to white spots, toenail psoriasis can cause tiny dents or pits in the affected toenails, yellow or brown discoloration, thick white buildup under the toenail, blood under the nail, crumbling toenails and toenails that separate from the skin of the nailbed. Nail psoriasis presents in a number of ways – not just as white patches on toenails. Toenail PsoriasisĪpproximately 80 to 90 percent of people with psoriasis develop nail psoriasis, though it’s possible to have nail psoriasis without exhibiting signs of the skin condition. If you’re experiencing any of these symptoms, it’s important to see a podiatrist for diagnosis and treatment as soon as possible to stop the toenail fungus in its tracks before developing complications, such as swelling, pain, and bleeding around the nails, difficulty walking or more serious infection (particularly if you’re diabetic). The infection can even spread to the skin between the toes and other parts of your feet, which is commonly called athlete’s foot (tinea pedis). ![]() If the toenail fungus progresses, it can go deeper into the nail, causing discoloration, thick white stuff under the toenail (keratin debris), nail thickening and crumbling, and even transmission to surrounding nails. A toenail fungal infection typically presents as a white or yellow-brown spot under the tip or side of your toenail and, if mild, may resolve on its own. Officially called onychomycosis, nail fungus is a common cause of white spots on toenails. ![]() ![]() ![]() You can do this in your System Preferences > Security & Privacy > Privacy > Screen Recording. Note: On Mac OS 10.15 Catalina, you need to allow Zoom access to screen recording to share your screen. If you are using a dual monitor set-up, you can turn on the Use Dual Monitors feature to see the screen sharing on one monitor and participants on the second. If set to show, the participant’s name will briefly display beside their annotation.Įnd Meeting: Leave the meeting or end the meeting for all participants. The meeting host or co-host can choose to split the participants of the meeting into these separate sessions automatically or manually, or they can allow participants to select and enter breakout sessions as they please. ![]() Show/Hide Names of Annotators: Show or hide the participants’ name when they are annotating on a screen share. Last Updated: JMeeting breakout rooms allow you to split your Zoom meeting in up to 50 separate sessions. Record: Start recording locally or to the cloud.Īllow/Disable participants annotation: Allow or prevent the participants from annotating on your shared screen. Invite: Invite others to join the meeting. More: Hover over more for additional options. Pause Share: Pause your current shared screen.Īnnotate / Whiteboard: Display annotation tools for drawing, adding text, etc. You will be prompted to select which screen you want to share again. Participants/Manage Participants: View or manage the participants (if the host). Start/Stop Video: Start or stop your in-meeting video. Mute/Unmute: Mute or unmute your microphone. When you start sharing your screen, the meeting controls will move into a menu that you can drag around your screen. To disable automatic full screen when viewing a shared screen, disable this option in your desktop client settings: Enter full screen automatically when a participant shares screen.Ĥ.To exit full-screen, click Exit Full Screen in the top-right corner or press the Esc key. Zoom will automatically switch to full screen to optimize the shared screen view.Do not check this otherwise, as it may cause the shared screen to be blurry. Check Optimize for full screen video clip: Check this if you will be sharing a video clip in full screen mode.Check Share Computer Sound: If you check this option, any sound played by your computer will be shared in the meeting.You can also choose an individual application that is already open on your computer, the desktop, a whiteboard, or an iPhone/iPad.įor instructions on how to Share Powerpoint, See this page Click the Share Screen button located in your meeting controls.Ģ.Consider allowing students to annotate a file that you share so that they can practice the skill you are teaching.If you would like to share your annotations with students after the Zoom meeting, use the Save option in the annotation toolbar to keep the file along with any annotations you have made.Zoom annotate features can be used to demonstrate skills for your class or to collectively practice activities, such as close reading, case analysis, or analyzing images.Save the file with annotations by clicking on the Save option in the annotation toolbar.You can continue annotating by selecting Annotate again.You can stop annotating at any time by simply clicking the red X in the top left corner of the annotation toolbar.This will give you the option to clear all annotations, only your annotations, or just the annotations of other participants. If you would like to clear annotations, select the Clear icon from the annotation toolbar.You can also have Zoom Show Names of Annotators as they mark up. Draw is perhaps the most useful option, as it allows you to highlight text or images and circle objects. To do so, click the More button in the sharing toolbar and select Enable Annotation for Others. A toolbar will open with several annotation options.Click Annotate from the main toolbar, which likely moved to the top of your screen after you began sharing your screen.Your selected PDF will now be open and shared with other meeting participants.Click on the PDF you would like to annotate from the popup box.Within your Zoom session, click Share Screen in the lower toolbar. ![]()
![]() I am an RC pilot and I find the physics works well and the graphics run smoothly on my iMac and MacBook Pro. The download size is very large and will take several hours to complete!Īs long as you do not have any need to work with customer service you will probably like this simulator. Some of the complex 4D sceneries require a fast graphic card for optimal performance. Intel HD Graphics 3000, Intel HD Graphics 4000 or Intel Iris Pro or faster.NVIDIA GeForce 9600, 320M, 330M or faster with 512 MB or more.The Intel integrated graphic cards GMA 950 and GMA X3100 IMPORTANT, the following graphic cards are NOT supported: For the best experience, we strongly recommend to use a joystick or dedicated R/C controller with 4 axes. In-App purchases available: Upgrade aerofly RC 7 to the Professional Edition ( 170 models / 40 sceneries ) or Ultimate Edition ( 200 models / 50 sceneries ) both including additional features like freely scalable models, aircraft editor, helicopter hover trainer and torque-trainer.Īll models can be flown using the mouse and keyboard only.Suitable for many R/C transmitters and joysticks.Fly with friends all over the world in Multiplayer Mode.Different model types: Quadrocopters, electric and gas powered airplanes, helicopters, gliders, jets, and scale models.Set wind and time of day for challenging training conditions.Stunning dynamics simulation for a realistic flight feeling.Highly detailed aircraft with state of the art physics simulation.Awesome sceneries with full Retina Display support.Choose from over 30 models and 5 sceneries (Standard Edition).The Ultimate edition features more than 200 models and over 50 sceneries! ![]() However you may upgrade your edition at any time by purchasing an upgrade to the Professional or Ultimate edition using In-App purchases. This edition is a good starting into radio controlled flying. ![]() When you buy this App you will have aerofly RC 7 Standard Edition with a choice of 30 different models and 5 different sceneries. Many features and game-like competitions will test your piloting abilities that put real fun into your virtual flying!Īerofly RC 7 is available in three different editions. You may choose from a wide variety of models, like aerobatic airplanes, helicopters, jets, gliders, scale models and quadrocopters.Īfter practicing on aerofly RC 7, you’ll fly confidently and instinctively at the field. Together with our superb model details and awesome scenery quality you will feel as if standing on a real flying field. Our state of the art physics simulation gives you a stunning level of realism. When it comes to learning and improving R/C flying skills, aerofly RC 7 is the number one choice for R/C pilots. Learn to fly radio controlled (R/C) models with aerofly RC 7. *** It is strongly recommended to use this software with a dedicated joystick or R/C controller with a least 4 independent axes *** *** Please Check System Requirements Prior to Purchasing *** ![]() ![]() These instruments can be very small like the trumpet and very large like the tuba. Most brass instruments are still made of brass or a similar metal, hence their name. Woodwind instruments include the flute, clarinet, bass clarinet, saxophone (alto, tenor, baritone, etc.), bassoon, oboe, and more.īrass instruments, like woodwinds, produce sound by blowing air into them, but brass musicians must vibrate their lips on a mouthpiece to create the distinct brass sound. ![]() ![]() Today, many woodwinds are made of metal and some are even made of plastic. Woodwinds get their name because early versions of these instruments were often made of wood and their sound is produced with wind or air. Flutes are played by blowing air across the mouthpiece hole, vibrating air within the instrument. Air is directed into reed instruments through a reed, which is a single or double strip of wood attached to the mouthpiece of an instrument, and the vibrations that result produce sound. Woodwinds are a diverse collection of instruments that can be further grouped into flutes and reed instruments. Woodwind instruments are played by blowing air into (or in the case of flutes, across) them. However you choose to classify keyboards and pianos is up to you, just be consistent. Keyboards and pianos are often considered percussion instruments because when their keys are depressed, tiny hammers within the large instrument strike their corresponding strings, but they can also be placed into their own family. Drums dating as far back as 5000 BC, constructed of animal hide and bone, have been discovered. Percussion instruments range in complexity from simple triangles to elaborate marimbas and everything in between. The percussion family includes drums, bongos, maracas, triangles, marimbas, cymbals, xylophones, and much more-this is one of the biggest groups of instruments. Percussion instruments produce sound when hit or shaken. You might choose to assume the role of a conductor if your class studies music. An orchestra or band is led by a conductor, also called a director. When a group of instruments play together, they are called an orchestra or band-usually, a band when there are no strings and an orchestra when there are. Teach these groups to your students to help them understand the mechanics of instrumentation and find the family that best suits them. Instruments are grouped into families determined by the material of which they are constructed and the way that their sound is produced. No matter what, all students should get to experience music instruction at some point in their education. If you don't have the funding for instruments, try making your own with your students. Teachers should do their best to make music a part of their students' lives. Studies have shown that art improves a student's ability to absorb and retain new information. ![]() Music instruction is an important part of any child's education because it improves language development and reasoning in addition to providing an artistic form of expression. Many schools now include music education in the general curriculum and even devote classes entirely to music. Some instruments date back to the dawn of time-an early flute-like instrument is one of the earliest recorded pieces of musical equipment. Music seems to have always been a part of human existence. ![]() ![]() ![]() While Apple didn’t make any bold claims in terms of gaming performance, the headset’s hardware should be more than capable enough at running some games that are on Mac. The Vision Pro features Apple’s M2 processor - the same one used in its latest laptops and desktops. ![]() Thanks to its ability to connect with your Mac, you’ll be able to view other games through it, too, assuming your Mac is powerful enough to run them. With gaming, you can position and resize the game screen to your liking within any room you’re in. In terms of gaming, the Vision Pro will be compatible with over 100 Apple Arcade games at launch, and it can connect to game controllers like Sony’s DualSense controller. Relatedly, Disney CEO Bob Iger appeared during Apple’s keynote to share that a special version of Disney Plus will be available on the Vision Pro that provides a vastly more info-rich experience, whether you’re watching sports or Star Wars. It’s also compatible with 3D movies, for all of you Avatar fans. The Vision Pro can also let you get immersed with movies and TV shows the headset can dim the surrounding field of view to make it look like you’re in a movie theater. To others in the FaceTime call, you’ll be represented as a “Persona” (not to be confused with the Atlus RPG series) that’s computationally generated with its internal cameras. Alternatively, it can be powered by your Mac.Īpple spent a lot of time talking about how the Vision Pro could become a big deal in the workspace, with its ability to show multiple screens, including FaceTime in augmented reality, within your room. Its battery can power the headset for up to two hours. Notably, the Vision Pro doesn’t have a built-in battery instead of trying to pack one in, which would have expanded its size and weight, the battery is external, and can be tucked in your pocket. The headset is able to show a 4K display of your Mac’s screen on its headset, if you’d prefer to work that way. You can use apps created for the Vision Pro, or use it to connect to your Mac wirelessly. If you’re busy while using the Vision Pro, onlookers will see a preview of your content laid over your eyes. Its most impressive (and conversation-starting) design feature is its glass-covered exterior that can display your eyes when there’s a person nearby. For instance, the Digital Crown used to control the opacity of your augmented view first appeared on the Apple Watch, albeit for a completely different purpose. The Vision Pro has an intriguing design that borrows elements from Apple’s other products. The Vision Pro has bottom-mounted cameras that allow it to track small hand gestures. ![]() However, it doesn’t operate with typical VR/AR controllers it relies on users’ eye movement, hand tracking, and voice to navigate its interface. ![]() Like the Meta Quest, the Vision Pro is a stand-alone headset running on its own platform, visionOS. Our sibling site The Verge has first-look impressions with the Vision Pro. Apple CEO Tim Cook debuted the high-end Vision Pro augmented reality headset at the WWDC 2023 keynote on Monday, of which it was the highlight announcement.Īpple’s Vision Pro headset will be released in early 2024, starting at a whopping $3,499. You can connect it to a PlayStation 5, too, but you’ll need to request a free adapter from Sony – something to consider if you’re planning on unboxing it over the holidays.After years of rumors suggesting that Apple would launch a virtual reality headset, that reality has arrived. PlayStation VR is unique among VR headsets in that it connects to your PlayStation 4 console as opposed to a beefy Windows PC. Also check out guide to the best PSVR space games to see what other games you should pick up. Whether it’s exploring the cosmos in No Man’s Sky, battling the Empire in Star Wars: Squadrons, or captaining a Starfleet vessel in Star Trek: Bridge Crew, games can be purchased on disc or via the PlayStation Store. There are plenty more VR space games available, too. That means the only thing missing is the console itself! You’ll also find Iron Man VR, which has a very respectable Metacritic score of 73, as well as a PlayStation VR demo collection that includes trial versions of PSVR megahits like the time-slowing shooter Superhot VR, adorable platformer Astrobot Rescue Mission, and rhythm action game Thumper VR. Inside the PlayStation VR Iron Man bundle you’ll find the PlayStation VR headset, as well as two PlayStation Move controllers and the PlayStation Camera, which is used for head-tracking. ![]() ![]()
![]() ![]() Some of the best apps for QuickBooks Desktop streamline the invoicing process for engineering firms. Send Invoices Faster for Engineering Firms QuickBooks desktop automation helps professional service firms improve their cash flow and reduce administrative costs by simplifying invoicing and billing with integrating software solutions for specific industries. Other applications, like printing shipping labels, only require one-way synchronization since once the shipping label is printed, there is no need to update the record. Mission-critical applications like CRM and accounting require two-way synchronization to keep client information up-to-date. Integrating applications provides value for your business by saving time and eliminating mistakes by removing the need to manually input data and avoiding the need to batch import or add data multiple times. The marketplace also features other apps for back-office applications for manufacturing, inventory management, shipping, logistics and point-of-sale solutions. There are connections with eCommerce tools for businesses to sell products online. Some of these integrations include connections to CRM software. The MarketPlace includes other QuickBooks add-ons to improve productivity and connect the accounting application with other technology. Everything must be saved in the software, and an audit trail must be available for the audit agency to review if required. You must also record employee overtime, employment training, and expenses. DCAA says employers must document workers and the amount of time they work on contract work. If your professional services firm works with government agencies, you know how important it is to have a timesheet configured to meet Defense Contract Audit Agency (DCAA) requirements. For custom requirements, developers can connect BigTime via the QuickBooks integration API. In addition to easy-to-use invoicing, time tracking and project management software, the QuickBooks Desktop app includes analytics and reporting dashboards, expense tracking and DCAA time tracking complying with government billing requirements.īigTime is one of the best invoicing apps that integrate with QuickBooks Desktop. The integrated platform provides several features sure to make professional services firms happy. You can find BigTime on the QuickBooks Marketplace for Desktop applications. Apps That Integrate With QuickBooks DesktopīigTime is an invoicing solution with QuickBooks integration with desktop and online versions. It also integrates with other QuickBooks apps. ![]() BigTime is a SaaS product that works with both QuickBooks’ Online and Desktop versions. BigTime is one of the best invoicing apps that work with QuickBooks and helps professional service teams manage their client workloads, invoicing and online payments without missing a beat. BigTime is a company based in Chicago with over 2,000 users and manages billions of dollars in client invoicing and payments. Integrating third-party apps to QuickBooks saves accounting staff time, improves transparency for account teams and improves the customer experience by providing self-service portals to pay bills and obtain project updates.Ī better solution is to use invoicing software that integrates with QuickBooks, CRM software and other customer-facing applications. Meanwhile, the account service team doesn’t have insights into invoicing and must bother the accounting team to check up on payment status to respond to client inquiries. Managing all of these disparate apps and processes adds up to administrative costs for accounting or bookkeepers to manage. Once the invoices are sent, customers use QuickBooks payments, credit cards or ACH services through online payment processors or banks. Many firms use multiple apps to manage these processes and then manually re-enter data into QuickBooks to generate invoices. Tracking employee time on customer projects needs to roll up into invoicing every month. Account managers often need to produce estimates based on internal human resources. In a professional services firm, invoicing is an integral part of customer service. ![]() QuickBooks is a great bookkeeping app, but if your account management team needs to track time, manage projects and do invoicing, then providing them with direct access to QuickBooks isn’t practical. Many professional service firms rely on QuickBooks as their accounting and invoicing software. ![]() ![]() ![]() Initiation of regeneration from a remaining axon stump has been observed in many types of neurons in vivo, including interneurons in the mouse spinal cord, interneurons in snails, motor neurons in C.elegans and Drosophila and sensory neurons in C. In some cases, particularly in the peripheral nervous system, regrowing axons may ultimately reconnect with targets to recover function. Classic axon regeneration involves signaling from the site of injury back to the cell body, followed by initiation of outgrowth from the remaining axon stump. In response to axon severing, many neurons have the capacity to regenerate this part of the cell. We conclude that both ddaE and ddaC can regenerate axons either from the stump or a dendrite, and that there is some feedback between the two sites that modulates dendritic microtubule polarity. However, changes in dendritic microtubule polarity differed in response to the two types of injury, and were influenced by the presence of a scar at the distal axotomy site. A transcriptional reporter for axon injury signaling, puc-GFP, increased with similar timing and levels after proximal and distal axotomy. Because cutting the axon close to the cell body results in growth of the new axon from a dendrite, and cutting further out may not, we asked whether the initial response in the cell body was similar after both types of injury. We next demonstrated if a stump remains, new axons can originate from this site and a dendrite at the same time. We also showed that ddaC neurons regenerate from the dendrite when the axon is severed close to the cell body. We found that ddaE neurons can initiate regeneration from an axon stump when a stump remains. To provide a more complete picture of axon regeneration in these cell types, we performed additional injury types. In Drosophila, it has been shown that a complex sensory neuron, ddaC, can regenerate an axon from a stump, and a simple sensory neuron, ddaE, can regenerate an axon from a dendrite. ![]() Methodsĭrosophila sensory neurons are ideal for studying neuronal injury responses because they can be injured reproducibly in a variety of genetic backgrounds. However, in many mammalian neurons, new axons initiate from a dendritic site when the axon is injured close to the cell body. New outgrowth often originates from the remaining axon stump. After axon severing, neurons recover function by reinitiating axon outgrowth. ![]() |
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